Article
Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population.
Stroke - 1 Oct 2005
Saleheen Danish, Bukhari Shabbar, Haider Shajjia Razi, Nazir Aisha, Khanum Shaheen, Shafqat Saad, Anis M Kashif, Frossard Philippe
Abstract excerpt
BACKGROUND AND OBJECTIVES: Identification of STRK1 locus by the deCODE group followed by the discovery of phosphodiesterase 4D (PDE4D) gene in strong association with ischemic stroke patients has provided useful insights toward understanding the genetic etiology of the disease. In this study, we aimed at investigating the association between 3 polymorphisms of the PDE4D gene and ischemic stroke in the Pakistani...
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