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Mouse germ cells go through typical epigenetic modifications after intratesticular tissue grafting

6 Oct 2011

Abstract excerpt

BACKGROUND: Since spermatogonial stem cell transplantation (SSCT) and testicular tissue grafting (TTG) may have important clinical applications, the safety of these promising techniques has to be proved. This study was designed to characterize epigenetic modifications in prepubertal and adult mouse germ cells and to study these epigenetic mechanisms after SSCT and TTG. METHODS: Testicular cell suspensions were...

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PMID: 21984576
DOI: 10.1093/humrep/der334

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