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[Association between diversity of hypoxia at different altitude and the polymorphism of EPAS1 gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2011

Ke Jin-kun, Yao Yu-feng, Liu Shu-yuan, Shi Lei, Yu Liang, Lin Ke-qin, Tao Yu-fen, Shi Li, Yi Wen, Huang Xiao-qin, Chu Jia-you

Abstract excerpt

OBJECTIVE: To study the selection effect of endothelial PAS domain protein 1 (EPAS1) gene induced by high altitude hypoxia environment. METHODS: Fourteen single nucleotide polymorphism sites (SNPs) of the EPAS1 gene were genotyped using PCR-restriction fragment length polymorphism (PCR-RFLP) in three Tibetan groups (58 samples from Tibetan living in an altitude of about 3700 meters above sea level, 47 from...

Topics

Alleles
Altitude Sickness
Basic Helix-Loop-Helix Transcription Factors
China
Gene Frequency
Haplotypes
Humans
Hypoxia
Linkage Disequilibrium
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21983741
DOI: 10.3760/cma.j.issn.1003-9406.2011.05.026

Genes

EPAS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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