Article
Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes?
The journal of obstetrics and gynaecology research - 1 Oct 2008
Bienertová-Vasků Julie, Dostálová Zuzana, Kanková Katerina, Bienert Petr, Vasků Anna, Unzeitig Vít
Abstract excerpt
AIM: The pathophysiology of pre-eclampsia, one of the leading causes of maternal mortality worldwide, still remains unclear. Recently, it has been suggested that impaired regulation of complex interactions among various adipokines plays an important role in the development of pre-eclampsia. The aim of this study was to investigate whether the two common polymorphisms of the leptin (LEP) and adiponectin (APM1)...
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