Article
Acetylation regulates the stability of a bacterial protein: growth stage-dependent modification of RNase R.
Molecular cell - 7 Oct 2011
Liang Wenxing, Malhotra Arun, Deutscher Murray P
Abstract excerpt
RNase R, an Escherichia coli exoribonuclease important for degradation of structured RNAs, increases 3- to 10-fold under certain stress conditions, due to an increased half-life for this usually unstable protein. Components of the trans-translation machinery, tmRNA, and its associated protein, SmpB, are essential for RNase R instability. However, it is not understood why exponential phase RNase R is unstable or...
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