Article
ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples.
BMC bioinformatics - 6 Oct 2011
Mordelet Fantine, Vert Jean-Philippe
Abstract excerpt
BACKGROUND: Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene candidates, the identification of disease genes among the candidates remains time-consuming and expensive. Efficient computational methods are therefore needed to...
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