Article
Kernel-based data fusion for gene prioritization.
Bioinformatics (Oxford, England) - 1 Jul 2007
De Bie Tijl, Tranchevent Léon-Charles, van Oeffelen Liesbeth M M, Moreau Yves
Abstract excerpt
MOTIVATION: Hunting disease genes is a problem of primary importance in biomedical research. Biologists usually approach this problem in two steps: first a set of candidate genes is identified using traditional positional cloning or high-throughput genomics techniques; second, these genes are further investigated and validated in the wet lab, one by one. To speed up discovery and limit the number of costly wet...
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