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Article

Disease gene prioritization using network and feature.

Journal of computational biology : a journal of computational molecular cell biology - 1 Apr 2015

Xie Bingqing, Agam Gady, Balasubramanian Sandhya, Xu Jinbo, Gilliam T Conrad, Maltsev Natalia, Börnigen Daniela

Abstract excerpt

Identifying high-confidence candidate genes that are causative for disease phenotypes, from the large lists of variations produced by high-throughput genomics, can be both time-consuming and costly. The development of novel computational approaches, utilizing existing biological knowledge for the prioritization of such candidate genes, can improve the efficiency and accuracy of the biomedical data analysis. It...

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Identifiers

PMID: 25844670
DOI: 10.1089/cmb.2015.0001
PMCID: PMC4808289

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