Article
NMR studies of interactions of ligands with dihydrofolate reductase.
Biochemical pharmacology - 1 Jul 1990
Feeney J
Abstract excerpt
NMR spectroscopy is a useful technique for studying interactions, conformations and dynamic processes within ligand-protein complexes. Several examples of the application of the method to studies of complexes of anti-folate drugs with their target enzyme, dihydrofolate reductase, are discussed.
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