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Article

Absence of APOL1 risk variants protects against HIV-associated nephropathy in the Ethiopian population.

American journal of nephrology - 1 Jan 2011

Behar Doron M, Kedem Eynat, Rosset Saharon, Haileselassie Yonas, Tzur Shay, Kra-Oz Zipi, Wasser Walter G, Shenhar Yotam, Shahar Eduardo, Hassoun Gamal, Maor Carcom, Wolday Dawit, Pollack Shimon, Skorecki Karl

Abstract excerpt

BACKGROUND: Susceptibility to end-stage kidney disease (ESKD) among HIV-infected Americans of African ancestral heritage has been attributed to APOL1 genetic variation. We determined the frequency of the APOL1 G1 and G2 risk variants together with the prevalence of HIV-associated nephropathy (HIVAN) among individuals of Ethiopian ancestry to determine whether the kidney disease genetic risk is PanAfrican or...

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Source

Identifiers

PMID: 21968148
DOI: 10.1159/000332378

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HIV-associated nephropathy in African Americans11The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. The publisher or recipient acknowledges right of the U.S. Government to retain a nonexclusive, royalty-free license in and to any copyright covering the article.Semantic proximity Read ↗

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