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Article

Comparative genetics of the poly-Q tract of ataxin-1 and its binding protein PQBP-1.

Biochemical genetics - 1 Apr 2012

Kurosaki Tatsuaki, Gojobori Jun, Ueda Shintaroh

Abstract excerpt

Human PQBP-1 is known to interact with triplet repeat disease gene products such as ataxin and huntingtin through their poly-glutamine (poly-Q) tracts. The poly-Q tracts show extensive variation in both the number and the configuration of repeats among species. A surface plasmon resonance assay showed clear interaction between human PQBP-1 and Q(11), representative of the poly-Q tract of the ataxin-1 of Old World...

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Identifiers

PMID: 21964520
DOI: 10.1007/s10528-011-9473-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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