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Article

Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder.

Pharmacogenomics - 1 Nov 2011

Squassina Alessio, Manchia Mirko, Borg Joseph, Congiu Donatella, Costa Marta, Georgitsi Marianthi, Chillotti Caterina, Ardau Raffaella, Mitropoulos Konstantinos, Severino Giovanni, Del Zompo Maria, Patrinos George P

Abstract excerpt

AIMS: Bipolar disorder (BD) is a lifelong psychiatric illness characterized by manic and depressive episodes affecting 1-5% of the general population. Among mood-stabilizing treatments, lithium represents the mainstay in the therapeutic management of BD. However, besides the relatively high rate of excellent responders, a significant fraction of patients present patterns of partial or nonresponse to lithium. This...

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PMID: 21961650
DOI: 10.2217/pgs.11.102

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Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder.PMID 21961650Read ↗

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