Article
[Control of the mutagenicity of a new immunomodulator].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Mar 1990
Volgareva G M, Savranskaia S Ia, Tolcheev Iu D, Anpilogova O R
Abstract excerpt
New immunostimulator STP, peptide isolated from the cultivation medium of Streptococcus species producer strain TOM-1606 by chromatographic purification, was controlled for mutagenicity. The preparation, introduced into mice in doses of 6.7 X 10(2) - 6.7 X 10(4) micrograms/kg, i.e. exceeding the...
Topics
- Adjuvants, Immunologic
- Animals
- Bone Marrow
- Dose-Response Relationship, Drug
- Erythrocytes
- Male
- Mice
- Micronucleus Tests
- Mutagenicity Tests
- Mutation
- Peptides
- Salmonella typhimurium
- Streptococcus
- Time Factors
