Article
[Control of the mutagenicity of a new immunomodulator].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Mar 1990
Volgareva G M, Savranskaia S Ia, Tolcheev Iu D, Anpilogova O R
Abstract excerpt
New immunostimulator STP, peptide isolated from the cultivation medium of Streptococcus species producer strain TOM-1606 by chromatographic purification, was controlled for mutagenicity. The preparation, introduced into mice in doses of 6.7 X 10(2) - 6.7 X 10(4) micrograms/kg, i.e. exceeding the stimulating dose 1000-fold, did not induce the appearance of micronuclei in polychromatophilic erythrocytes of the...
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