Article
[Bacterial test-system for a primary screening of the substances with potential anti-cancer activity].
TSitologiia i genetika - 1 Jan 2000
Pererva T P, Dvornik A S, Miriuta A Iu, Mozhilevskaia L P, Kunakh V A
Abstract excerpt
A principle possibility of antitumour activity test in bacterial system represented by Escherichia coil of the wild type and its MS2-induced mutant has been shown. The initial bacterial strain is an indicator of toxic properties of the tested substances and the mutant one is a specific test-culture modelling a tumour cell. The comparison of the data described for eucaryotes with the data obtained using the...
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