Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of genomic sequence variability on quantitative PCR assays for diagnosis of polyomavirus BK infection.

Journal of clinical microbiology - 1 Dec 2011

Randhawa P, Kant J, Shapiro R, Tan H, Basu A, Luo C

Abstract excerpt

Knowledge of polyomavirus BK (BKV) genomic diversity has greatly expanded. The implications of BKV DNA sequence variation for the performance of molecular diagnostic assays is not well studied. We analyzed 184 publically available VP-1 sequences encompassing the BKV genomic region targeted by an in-house quantitative hydrolysis probe-based PCR assay. A perfect match with the PCR primers and probe was seen in 81...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BK Virus
Share to DNA Primers
Share to Molecular Diagnostic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oligonucleotide Probes

Share to Polyomavirus Infections

Share to Sensitivity and Specificity

Share to Viral Load

Share to Virology

Source

Open in PubMed Open full text

Identifiers

PMID: 21956980
DOI: 10.1128/JCM.01230-11
PMCID: PMC3232941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of genomic sequence variability on quantitative PCR assays for diagnosis of polyomavirus BK infection.PMID 21956980Read ↗

Marked Variability of BK Virus Load Measurement Using Quantitative Real-Time PCR among Commonly Used AssaysSemantic proximity Read ↗

Genotyping of polyomavirus BK by Real Time PCR for VP1 gene.Semantic proximity Read ↗

Sequence Variation in Amplification Target Genes and Standards Influences Interlaboratory Comparison of BK Virus DNA Load Measurement.Semantic proximity Read ↗

Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation PatientsSemantic proximity Read ↗

Quantification of plasma BK polyomavirus loads is affected by sequence variability, amplicon length, and non-encapsidated viral DNA genome fragments.Semantic proximity Read ↗

DNA sequencing of viral capsid protein VP-1 region in patients with BK virus interstitial nephritis.Semantic proximity Read ↗

Single-nucleotide polymorphisms within the BK polyomavirus non-coding control region are genotype-associatedSemantic proximity Read ↗

VP-1 quasispecies in human infection with polyomavirus BK.Semantic proximity Read ↗

Prevalence and molecular characterization of BK polyomavirus genotypes based on VP1 gene from renal transplant patients in Pakistan.Semantic proximity Read ↗

Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study.Semantic proximity Read ↗

Reevaluating and Optimizing Polyomavirus BK and JC Real-Time PCR Assays To Detect Rare Sequence PolymorphismsSemantic proximity Read ↗

Phylogenetic analysis of polyomavirus BK sequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.