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Single-nucleotide polymorphisms within the BK polyomavirus non-coding control region are genotype-associated

24 Jun 2025

Abstract excerpt

family. The BKPyV genome is divided into three regions, including the non-coding control region (NCCR), the early region, and the late region. BKPyV has one of the highest mutation rates among DNA viruses, and four genotypes have been identified based on amino acid variation within the VP1 region. Mutations within the NCCR have been noted, and this region exhibits hypervariability. Here, we show that many of the...

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PMID: 40552811
DOI: 10.1128/spectrum.00494-25

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