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Article

Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Mar 2012

Matsuo Keitaro, Rossi Marta, Negri Eva, Oze Isao, Hosono Satoyo, Ito Hidemi, Watanabe Miki, Yatabe Yasushi, Hasegawa Yasuhisa, Tanaka Hideo, Tajima Kazuo, La Vecchia Carlo

Abstract excerpt

Folate consumption is inversely associated with the risk of oral and pharyngeal cancer (OPC) and potentially interacts with alcohol drinking in the risk of OPC. Aldehyde dehydrogenase 2 (ALDH2) gene polymorphism is known to interact with alcohol consumption. The aim of this study was to investigate potential interaction between folate, alcohol drinking, and ALDH2 polymorphism in the risk of OPC in a Japanese...

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Source

Identifiers

PMID: 21946912
DOI: 10.1097/CEJ.0b013e32834c9be5

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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