Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prpE gene of Salmonella typhimurium LT2 encodes propionyl-CoA synthetase.

Microbiology (Reading, England) - 1 Jun 1999

Horswill Alexander R, Escalante-Semerena Jorge C

Abstract excerpt

Biochemical and genetic evidence is presented to demonstrate that the prpE gene of Salmonella typhimurium encodes propionyl-CoA synthetase, an enzyme required for the catabolism of propionate in this bacterium. While prpE mutants used propionate as carbon and energy source, prpE mutants that lacked acetyl-CoA synthetase (encoded by acs) did not, indicating that Acs can compensate for the lack of PrpE in prpE...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Coenzyme A Ligases
Share to Genes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mass Spectrometry

Share to Operon

Share to Repressor Proteins

Share to Saccharomyces cerevisiae Proteins

Share to Salmonella typhimurium

Source

Identifiers

PMID: 10411265
DOI: 10.1099/13500872-145-6-1381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prpE gene of Salmonella typhimurium LT2 encodes propionyl-CoA synthetase.PMID 10411265Read ↗

Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol.Semantic proximity Read ↗

Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle.Semantic proximity Read ↗

Identification of a new prp locus required for propionate catabolism in Salmonella typhimurium LT2.Semantic proximity Read ↗

2-Methylcitrate-dependent activation of the propionate catabolic operon (prpBCDE) of Salmonella enterica by the PrpR protein.Semantic proximity Read ↗

Molecular characterization of PrpR, the transcriptional activator of propionate catabolism in Corynebacterium glutamicum.Semantic proximity Read ↗

prpR, ntrA, and ihf functions are required for expression of the prpBCDE operon, encoding enzymes that catabolize propionate in Salmonella enterica serovar typhimurium LT2.Semantic proximity Read ↗

Cobalamin-dependent 1,2-propanediol utilization by Salmonella typhimurium.Semantic proximity Read ↗

Studies of propionate toxicity in Salmonella enterica identify 2-methylcitrate as a potent inhibitor of cell growth.Semantic proximity Read ↗

The methylcitric acid pathway in Ralstonia eutropha: new genes identified involved in propionate metabolism.Semantic proximity Read ↗

Residues C123 and D58 of the 2-methylisocitrate lyase (PrpB) enzyme of Salmonella enterica are essential for catalysis.Semantic proximity Read ↗

The alternative electron acceptor tetrathionate supports B12-dependent anaerobic growth of Salmonella enterica serovar typhimurium on ethanolamine or 1,2-propanediol.Semantic proximity Read ↗

Glutathione is required for maximal transcription of the cobalamin biosynthetic and 1,2-propanediol utilization (cob/pdu) regulon and for the catabolism of ethanolamine, 1,2-propanediol, and propionate in Salmonella typhimurium LT2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.