Article
Common variants in CRP and LEPR influence high sensitivity C-reactive protein levels in North Indians.
PloS one - 1 Jan 2011
Mahajan Anubha, Tabassum Rubina, Chavali Sreenivas, Dwivedi Om Prakash, Chauhan Ganesh, Ghosh Saurabh, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
BACKGROUND: High sensitivity C-reactive protein (hsCRP) levels are shown to be influenced by genetic variants in Europeans; however, little is explored in Indian population. METHODS: Herein, we comprehensively evaluated association of all previously reported genetic determinants of hsCRP levels, including 18 cis (proximal to CRP gene) and 73 trans-acting (distal to CRP gene) variants in 4,200 North Indians of...
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