Article
Contribution of serotype and genetic background to virulence of serotype 3 and serogroup 11 pneumococcal isolates.
Infection and immunity - 1 Dec 2011
McAllister Lauren J, Ogunniyi Abiodun D, Stroeher Uwe H, Leach Amanda J, Paton James C
Abstract excerpt
The capsular serotype has long been associated with the virulence of Streptococcus pneumoniae. Here we present an in-depth study of phenotypic and genetic differences between serotype 3 and serogroup 11 S. pneumoniae clinical isolates from both the general and indigenous populations of Australia. Both serotypes/groups included clonally unrelated strains with differences in well-known polymorphic virulence genes,...
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