Article
SpliceAid 2: a database of human splicing factors expression data and RNA target motifs.
Human mutation - 1 Jan 2012
Piva Francesco, Giulietti Matteo, Burini Alessandra Ballone, Principato Giovanni
Abstract excerpt
Splicing is the most frequently altered biological process by mutations within gene regions. Information for splicing is recognized by several factors that bind pre-mRNA sequence and, through coordinated interaction, yield mature transcripts. Some in silico methods have been developed to predict if a mutation leads to aberrant splicing patterns. We previously created SpliceAid tool that is able to minimize false...
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