Article
Human Splicing Finder: an online bioinformatics tool to predict splicing signals.
Nucleic acids research - 1 May 2009
Desmet François-Olivier, Hamroun Dalil, Lalande Marine, Collod-Béroud Gwenaëlle, Claustres Mireille, Béroud Christophe
Abstract excerpt
Thousands of mutations are identified yearly. Although many directly affect protein expression, an increasing proportion of mutations is now believed to influence mRNA splicing. They mostly affect existing splice sites, but synonymous, non-synonymous or nonsense mutations can also create or disrupt splice sites or auxiliary cis-splicing sequences. To facilitate the analysis of the different mutations, we designed...
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