Article
SpliceDisease database: linking RNA splicing and disease.
Nucleic acids research - 1 Jan 2012
Wang Juan, Zhang Jie, Li Kaibo, Zhao Wei, Cui Qinghua
Abstract excerpt
RNA splicing is an important aspect of gene regulation in many organisms. Splicing of RNA is regulated by complicated mechanisms involving numerous RNA-binding proteins and the intricate network of interactions among them. Mutations in cis-acting splicing elements or its regulatory proteins have been shown to be involved in human diseases. Defects in pre-mRNA splicing process have emerged as a common...
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