Article
Assessing and managing risk when sharing aggregate genetic variant data.
Nature reviews. Genetics - 16 Sept 2011
Craig David W, Goor Robert M, Wang Zhenyuan, Paschall Justin, Ostell Jim, Feolo Michael, Sherry Stephen T, Manolio Teri A
Abstract excerpt
Access to genetic data across studies is an important aspect of identifying new genetic associations through genome-wide association studies (GWASs). Meta-analysis across multiple GWASs with combined cohort sizes of tens of thousands of individuals often uncovers many more genome-wide associated loci than the original individual studies; this emphasizes the importance of tools and mechanisms for data sharing....
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