Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypogonadotropic hypogonadism in a homozygous MC4R mutation carrier and the effect of sibutramine treatment on body weight and obesity-related health risks.

Obesity facts - 1 Jan 2011

Hainerová Irena Aldhoon, Zamrazilová Hana, Sedláčková Dana, Hainer Vojtěch

Abstract excerpt

OBJECTIVE: The first aim of our study was to define the hypogonadism manifested by low testosterone levels and incomplete male secondary sex characteristics in a 20-year-old male homozygous MC4R mutation carrier (G181D). The second aim of our study was to evaluate the effect of the anti-obesity drug sibutramine in this patient who failed to respond to an intensive lifestyle intervention and exhibited continuous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Composition
Share to Body Weight

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gonadotropins

Share to Hypogonadism

Share to Metabolic Diseases

Share to Sex Characteristics

Share to Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 21921657
DOI: 10.1159/000330763
PMCID: PMC6444747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypogonadotropic hypogonadism in a homozygous MC4R mutation carrier and the effect of sibutramine treatment on body weight and obesity-related health risks.PMID 21921657Read ↗

Novel KISS1 Gene Mutation Leading to Male Hypogonadotropic Hypogonadism.Semantic proximity Read ↗

Treatment options for children with monogenic forms of obesity.Semantic proximity Read ↗

[The genetics of hypogonadotropic hypogonadism in the male].Semantic proximity Read ↗

HYPOGONADOTROPIC HYPOGONADISMSemantic proximity Read ↗

Alteration of gastric functions and candidate genes associated with weight reduction in response to sibutramine.Semantic proximity Read ↗

Determination and regulation of body composition in elite athletes.Semantic proximity Read ↗

Successful treatment with atomoxetine of an adolescent boy with attention deficit/hyperactivity disorder, extreme obesity, and reduced melanocortin 4 receptor function.Semantic proximity Read ↗

A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults.Semantic proximity Read ↗

Dynamic GnRH and hCG testing: establishment of new diagnostic reference levels.Semantic proximity Read ↗

Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene.Semantic proximity Read ↗

Acquired hypoprolactinemia in men, possible phenotype.Semantic proximity Read ↗

[Isolated hypogonadotropic hypogonadism].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.