Article
HIV type 1 subtype diversity and drug resistance among HIV type 1-infected Kenyan patients initiating antiretroviral therapy.
AIDS research and human retroviruses - 1 Dec 2009
Lihana Raphael W, Khamadi Samoel A, Lubano Kizito, Lwembe Raphael, Kiptoo Michael K, Lagat Nancy, Kinyua Joyceline G, Okoth Fredrick A, Songok Elijah M, Makokha Ernest P, Ichimura Hiroshi
Abstract excerpt
The treatment of HIV-1 infection with antiretroviral drugs has greatly improved the survival of those who are infected. However, HIV-1 diversity and drug resistance are major challenges in patient management, especially in resource-poor countries. To evaluate HIV-1 genetic diversity and drug resistance-associated mutations among drug-naive patients in Kenya prior to antiretroviral therapy (ART), a genetic...
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