Article
Impact of human immunodeficiency virus type-1 sequence diversity on antiretroviral therapy outcomes.
Viruses - 20 Oct 2014
Langs-Barlow Allison, Paintsil Elijah
Abstract excerpt
Worldwide circulating HIV-1 genomes show extensive variation represented by different subtypes, polymorphisms and drug-resistant strains. Reports on the impact of sequence variation on antiretroviral therapy (ART) outcomes are mixed. In this review, we summarize relevant published data from both resource-rich and resource-limited countries in the last 10 years on the impact of HIV-1 sequence diversity on...
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