Article
Role of genes and environments for explaining Alzheimer disease.
Archives of general psychiatry - 1 Feb 2006
Gatz Margaret, Reynolds Chandra A, Fratiglioni Laura, Johansson Boo, Mortimer James A, Berg Stig, Fiske Amy, Pedersen Nancy L
Abstract excerpt
CONTEXT: Twin studies using selected samples have shown high heritability for Alzheimer disease (AD). OBJECTIVE: To evaluate genetic and environmental influences on AD in a fully ascertained population of older twins, including like- and unlike-sex pairs. DESIGN: Five-group quantitative genetic model: male monozygotic twins, female monozygotic twins, male dizygotic twins, female dizygotic twins, and unlike-sex...
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