Article
Replication study supports CTNND2 as a susceptibility gene for high myopia.
Investigative ophthalmology & visual science - 21 Oct 2011
Lu Boyu, Jiang Dan, Wang Panfeng, Gao Yang, Sun Wenmin, Xiao Xueshan, Li Shiqiang, Jia Xiaoyun, Guo Xiangming, Zhang Qingjiong
Abstract excerpt
PURPOSE: The CTNND2 gene is located in the linkage interval of high myopia locus MYP16 and two single-nucleotide polymorphisms (SNPs; rs6885224 and rs12716080) in CTNND2 were recently shown to associate with high myopia. This study evaluated such associations in an independent case-control series. METHODS: A total of 2773 unrelated individuals were enrolled in this study, including 1203 subjects with high myopia...
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