Proteomic Analysis of Virus-Host Interactions in an Infectious Context Using Recombinant Viruses

Abstract excerpt

RNA viruses exhibit small-sized genomes encoding few proteins, but still establish complex networks of interactions with host cell components to achieve replication and spreading. Ideally, these virus-host protein interactions should be mapped directly in infected cell culture, but such a high standard is often difficult to reach when using conventional approaches. We thus developed a new strategy based on...

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