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Article

Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection.

Scientific reports - 13 Jan 2021

Esoh Kevin K, Apinjoh Tobias O, Nyanjom Steven G, Wonkam Ambroise, Chimusa Emile R, Amenga-Etego Lucas, Amambua-Ngwa Alfred, Achidi Eric A

Abstract excerpt

Inferences from genetic association studies rely largely on the definition and description of the underlying populations that highlight their genetic similarities and differences. The clustering of human populations into subgroups (population structure) can significantly confound disease associations. This study investigated the fine-scale genetic structure within Cameroon that may underlie disparities observed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33441574
DOI: 10.1038/s41598-020-79124-1
PMCID: PMC7807043

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