Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.

doi:10.1093/hmg/ddr414

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Article

Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.

Human molecular genetics - 15 Dec 2011

Huffman Jennifer E, Knezevic Ana, Vitart Veronique, Kattla Jayesh, Adamczyk Barbara, Novokmet Mislav, Igl Wilmar, Pucic Maja, Zgaga Lina, Johannson Åsa, Redzic Irma, Gornik Olga, Zemunik Tatijana, Polasek Ozren, Kolcic Ivana, Pehlic Marina, Koeleman Carolien A M, Campbell Susan, Wild Sarah H, Hastie Nicholas D, Campbell Harry, Gyllensten Ulf, Wuhrer Manfred, Wilson James F, Hayward Caroline, Rudan Igor, Rudd Pauline M, Wright Alan F, Lauc Gordan

Abstract excerpt

The majority of human proteins are post-translationally modified by covalent addition of one or more complex oligosaccharides (glycans). Alterations in glycosylation processing are associated with numerous diseases and glycans are attracting increasing attention both as disease biomarkers and as targets for novel therapeutic approaches. Using a recently developed high-throughput high-performance liquid...

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Identifiers

PMID: 21908519
DOI: 10.1093/hmg/ddr414

Genes

MGAT5
FUT3
FUT6
FUT8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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