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Article

Critical role of laser microdissection for genetic, epigenetic and proteomic analyses in pancreatic cancer

1 Sept 2011

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, and molecular studies to unravel novel biomarkers and therapeutic targets are warranted. However, PDAC is characterized by different precursor lesions, as well as by an intense desmoplastic reaction, with islet of neoplastic cells often representing a minor population. Moreover, normal ductal cells, which are considered to be the normal counterpart of...

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PMID: 21902531
DOI: 10.1586/erm.11.62

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