Article
Triple-negative phenotype is of adverse prognostic value in patients treated with dose-dense sequential adjuvant chemotherapy: a translational research analysis in the context of a Hellenic Cooperative Oncology Group (HeCOG) randomized phase III trial.
Cancer chemotherapy and pharmacology - 1 Feb 2012
Skarlos P, Christodoulou C, Kalogeras K T, Eleftheraki A G, Bobos M, Batistatou A, Valavanis C, Tzaida O, Timotheadou E, Kronenwett R, Wirtz R M, Kostopoulos I, Televantou D, Koutselini E, Papaspirou I, Papadimitriou C A, Pectasides D, Gogas H, Aravantinos G, Pavlidis N, Arapantoni P, Skarlos D V, Fountzilas G
Abstract excerpt
PURPOSE: It is well recognized that breast cancer is a heterogeneous disease. The purpose of the current study was to classify patients according to the immunohistochemical phenotype of their tumors in an effort to evaluate the outcome of the respective groups of patients and specifically of thos...
Topics
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols
- Breast Neoplasms
- Chemotherapy, Adjuvant
- Clinical Trials, Phase III as Topic
- Cluster Analysis
- Disease-Free Survival