Article
Basal STAT3 activities are negatively correlated with tumor size in papillary thyroid carcinomas.
Journal of endocrinological investigation - 1 Apr 2012
Kim W G, Choi H-J, Kim W B, Kim E Y, Yim J H, Kim T Y, Gong G, Kim S Y, Chung N, Shong Y K
Abstract excerpt
BACKGROUNDS: Signal transducer and activators of transcription-3 (STAT3) plays a critical role in promoting survival and cell growth as well as facilitating angiogenesis and metastasis in several cancers. AIM: This investigation focused on evaluation of STAT3 activities in human papillary thyroid cancers (PTC). METHODS: STAT3 activities of nuclear extracts of tumor tissue were measured from 35 PTC patients using...
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