Gene environment interactions in bipolar disorder.

Abstract excerpt

It has been estimated that the heritable component of bipolar disorder ranges between 80 and 90%. However, even genome-wide association studies explain only a fraction of phenotypic variability not resolving the problem of "lost heritability". Although direct evidence for epigenetic dysfunction in bipolar disorder is still limited, methodological technologies in epigenomic profiling have advanced, offering even...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bipolar Disorder
• Share to Epigenomics
• Share to Genetic Predisposition to Disease