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Article

Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.

Human molecular genetics - 1 Dec 2011

Anderl Stefanie, Freeland Megan, Kwiatkowski David J, Goto June

Abstract excerpt

Epileptic seizures, particularly infantile spasms, are often seen in infants with tuberous sclerosis complex (TSC) soon after birth. It is feared that there are long-term developmental and cognitive consequences from ongoing, frequent epilepsy. In addition, the hallmark brain pathology of TSC, cortical tubers and giant cells are fully developed at late gestational ages. These observations have led us to examine...

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Identifiers

PMID: 21890496
DOI: 10.1093/hmg/ddr393
PMCID: PMC3209830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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