Article
[The effect of mutation him1 characterized by enhanced induced mutagenesis on the genetic effects of 6-N-hydroxylaminopurine in Saccharomyces cerevisiae].
Genetika - 1 Jan 1990
Ivanov E L, Sadykov S N, Koroleva I K
Abstract excerpt
The him1 mutation has been shown to influence the genetic effects of the mutagenic purine base analog 6-hydroxylaminopurine, i. e. inactivation of haploid cells, mutation induction, and inhibition of DNA synthesis in vivo. The influence observed is well consistent with the idea that the him1 mutation affects mismatch correction. We present evidence that during in vivo DNA replication 6-hydroxylaminopurine...
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