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A quantitative analysis of transcriptionally active syncytiotrophoblast nuclei across human gestation

24 Aug 2011

Abstract excerpt

The syncytiotrophoblast (STB) epithelial covering of the human placenta is a unique terminally differentiated, multi-nucleated syncytium. No mitotic bodies are observed in the STB, which is sustained by continuous fusion of underlying cytotrophoblast cells (CTB). As a result, STB nuclei are of different ages. Morphologically, they display varying degrees of chromatin compaction, suggesting progressive...

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PMID: 21883201
DOI: 10.1111/j.1469-7580.2011.01417.x

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