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Genetic animal models of schizophrenia related with the hypothesis of abnormal neurodevelopment.

Biological & pharmaceutical bulletin - 1 Jan 2011

Lu Lingling, Mamiya Takayoshi, Koseki Takenao, Mouri Akihiro, Nabeshima Toshitaka

Abstract excerpt

Accumulating evidence supports the existence of an overlap in genetic susceptibility with schizophrenia. Translation of human genetic mutations into animals is one of the most important strategies to study the pathogenesis of schizophrenia, identify potential drug targets, and test new medicines for antipsychotic treatment. Recent discoveries of susceptibility genes for schizophrenia make the possibility to...

Topics

Animals
Disease Models, Animal
Genetic Predisposition to Disease
Schizophrenia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21881217
DOI: 10.1248/bpb.34.1358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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