Article
Relation of the Fas and FasL gene polymorphisms with susceptibility to and severity of rheumatoid arthritis.
Rheumatology international - 1 Oct 2013
Yıldır Seyfi, Sezgin Melek, Barlas Ibrahim Ömer, Türköz Gözde, Ankaralı Handan Çamdeviren, Şahin Günşah, Erdal Mehmet Emin
Abstract excerpt
To investigate associations of the Fas and FasL genes polymorphisms with rheumatoid arthritis (RA). One hundred patients with RA and age-, sex- and ethnically matched 101 controls were included. Four polymorphisms of Fas (-670 A>G rs1800682, -1377 G>A rs2234767) and FasL (IVS2nt-124 A>G rs5030772, -844 T>C rs763110) genes were typed from genomic DNA. Genotype distributions and allelic frequencies were compared...
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