Article
Mechanisms of developmental regression in autism and the broader phenotype: a neural network modeling approach.
Psychological review - 1 Oct 2011
Thomas Michael S C, Knowland Victoria C P, Karmiloff-Smith Annette
Abstract excerpt
Loss of previously established behaviors in early childhood constitutes a markedly atypical developmental trajectory. It is found almost uniquely in autism and its cause is currently unknown (Baird et al., 2008). We present an artificial neural network model of developmental regression, exploring the hypothesis that regression is caused by overaggressive synaptic pruning and identifying the mechanisms involved....
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