Article
Synthesis and evaluation of compounds that induce readthrough of premature termination codons.
Bioorganic & medicinal chemistry letters - 1 Oct 2011
Jung Michael E, Ku Jin-Mo, Du Liutao, Hu Hailiang, Gatti Richard A
Abstract excerpt
A structure-activity relationship (SAR) study was carried out to identify novel, small molecular weight compounds which induce readthrough of premature termination codons. In particular, analogs of RTC13, 1, were evaluated. In addition, hypothesizing that these compounds exhibit their activity by...
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