Article
Development of mass cytometry methods for bacterial discrimination.
Analytical biochemistry - 1 Dec 2011
Leipold Michael D, Ornatsky Olga, Baranov Vladimir, Whitfield Chris, Nitz Mark
Abstract excerpt
Fluorescent flow cytometry has become the method of choice for interrogation of bacterial populations at the single-cell level. However, limitations of this technique include issues of dynamic range, spectral overlap, photobleaching, and overall low signal intensity due to the small size of bacteria. The recent development of mass cytometry allows single-cell analysis with the resolution of inductively coupled...
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