Article
New rabies virus variants for monitoring and manipulating activity and gene expression in defined neural circuits.
Neuron - 25 Aug 2011
Osakada Fumitaka, Mori Takuma, Cetin Ali H, Marshel James H, Virgen Beatriz, Callaway Edward M
Abstract excerpt
Glycoprotein-deleted (ΔG) rabies virus is a powerful tool for studies of neural circuit structure. Here, we describe the development and demonstrate the utility of new resources that allow experiments directly investigating relationships between the structure and function of neural circuits. New methods and reagents allowed efficient production of 12 novel ΔG rabies variants from plasmid DNA. These new rabies...
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