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Article

Molecular diagnosis of response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer.

Journal of the American College of Surgeons - 1 Jun 2011

Chen Zhenbin, Duldulao Marjun P, Li Wenyan, Lee Wendy, Kim Joseph, Garcia-Aguilar Julio

Abstract excerpt

BACKGROUND: Pathologic complete response (pCR) to neoadjuvant chemoradiation (CRT) is an important prognostic factor in locally advanced rectal cancer. However, it is uncertain if histopathological techniques accurately detect pCR. We tested a novel molecular approach for detecting pCR and compared it with current histopathological approaches. STUDY DESIGN: Pretreatment tumor biopsies and surgical specimens were...

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Identifiers

PMID: 21458303
DOI: 10.1016/j.jamcollsurg.2011.02.024
PMCID: PMC3104075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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