Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular karyotyping: from microscope to SNP arrays.

Hormone research in paediatrics - 1 Jan 2011

Gijsbers Antoinet C J, Ruivenkamp Claudia A L

Abstract excerpt

Chromosomal rearrangements are an important cause of distinctive and recognizable clinical phenotypes. For many years conventional karyotyping has been a successful tool to detect such chromosomal rearrangements. However, this technique has a limited resolution of 5-10 Mb. In the past decades, the development of new high-resolution techniques has led to the field of molecular cytogenetics. One of the most...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytogenetic Analysis
Share to Gene Expression Profiling
Share to Genetic Diseases, Inborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Karyotyping

Share to Microscopy

Share to Molecular Diagnostic Techniques

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 21865676
DOI: 10.1159/000330406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular karyotyping: from microscope to SNP arrays.PMID 21865676Read ↗

Human molecular cytogenetics: from cells to nucleotidesSemantic proximity Read ↗

Molecular karyotyping using an SNP array for genomewide genotyping.Semantic proximity Read ↗

Potentials and challenges of chromosomal microarray analysis in prenatal diagnosisSemantic proximity Read ↗

Detection of Chromosomal Aberrations in Clinical Practice: From Karyotype to Genome SequenceSemantic proximity Read ↗

Clinical utility of contemporary molecular cytogenetics.Semantic proximity Read ↗

Whole genome scanning as a cytogenetic tool in hematologic malignanciesSemantic proximity Read ↗

Optical genome mapping as a next-generation cytogenomic tool for detection of structural and copy number variations for prenatal genomic analysesSemantic proximity Read ↗

Single-nucleotide polymorphism array karyotyping in clinical practice: where, when, and how?Semantic proximity Read ↗

Cytogenetics in the genomics era: why karyotyping still mattersSemantic proximity Read ↗

Social and medical need for whole genome high resolution NIPTSemantic proximity Read ↗

Next generation cytogenetics: genome-imaging enables comprehensive structural variant detection for 100 constitutional chromosomal aberrations in 85 samplesSemantic proximity Read ↗

Optical Genome Mapping as a Next-Generation Cytogenomic Tool for Detection of Structural and Copy Number Variations for Prenatal Genomic AnalysesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.