Potentials and challenges of chromosomal microarray analysis in prenatal diagnosis

Abstract excerpt

Introduction: For decades, conventional karyotyping analysis has been the gold standard for detecting chromosomal abnormalities during prenatal diagnosis. With the development of molecular cytogenetic methods, this situation has dramatically changed. Chromosomal microarray analysis (CMA), a method of genome-wide detection with high resolution, has been recommended as a first-tier test for prenatal diagnosis,...

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• Share to Fetal and Pediatric Neurological Disorders
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