Article
Loss of heterozygosity mutations of tumor suppressor genes in cytologically atypical areas in chronic lymphocytic thyroiditis.
Endocrine pathology - 1 Jan 2002
Hunt Jennifer L, Baloch Zubair W, Barnes Leon, Swalsky Patricia A, Trusky Cindy L, Sesatomi E, Finkelstein Sydney, LiVolsi Virginia A
Abstract excerpt
The relationship between chronic lymphocytic thyroiditis (CLT) and papillary thyroid carcinoma (PTC) is a subject of controversy. Some investigators suggest a causal relationship, whereas others regard the two as only a coincidental occurrence. An additional complicating factor is the presence of atypical nuclei frequently found within lymphoid infiltrates in CLT, which resemble those in PTC. The finding of the...
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