Article
Hematopoietic stem cell transplantation with reduced intensity conditioning from a family haploidentical donor in an infant with familial hemophagocytic lymphohistocytosis.
International journal of hematology - 1 Sept 2011
Ohta Hideaki, Miyashita Emiko, Hirata Ikuko, Matsumura Risa, Yoshida Hisao, Hashii Yoshiko, Higashiura Takeshi, Yasumi Takahiro, Murata Yuuki, Heike Toshio, Yang Xi, Kanegane Hirokazu, Ohara Osamu, Ozono Keiichi
Abstract excerpt
Allogeneic hematopoietic stem cell transplantation is the only curative method for patients with familial hemophagocytic lymphohistiocytosis (FHL). We present a case of a 3-month-old girl with Munc13-4 mutation (FHL3), who underwent bone marrow transplantation (BMT) from her human leukocyte antigen-haploidentical mother following reduced intensity conditioning (RIC) with fludarabine, melphalan, and busulfan....
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